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Physical distancing markers and reminders are posted at a shopping mall in San Juan in this photo taken on June 16, 2020.  Gigie Cruz, ABS-CBN News

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Agence France-Presse

<div><span class="fr-img-caption fr-fic fr-dib" style="width:960px"><span class="fr-img-wrap"><img src="https://od2-image-api.abs-cbn.com/prod/editorImage/172115825411220200616-covid19-social-distancing-restroom-GCS-173634.jpg" style="width:960px" class="fr-fic fr-dib" alt="Physical distancing markers and reminders are posted at a shopping mall in San Juan in this photo taken on June 16, 2020.  Gigie Cruz, ABS-CBN News"/><span class="fr-inner" style="text-align:left">Physical distancing markers and reminders are posted at a shopping mall in San Juan in this photo taken on June 16, 2020.  <em>Gigie Cruz, ABS-CBN News</em></span></span></span><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">WASHINGTON -- Everybody poops sometimes, but does it really matter how often?</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">A new study published Tuesday in Cell Reports Medicine reveals that bowel movement frequency significantly influences physiology and long-term health, with the best outcomes linked with passing stools once or twice a day.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">Previous research has suggested associations between constipation and diarrhea with higher risks of infections and neurodegenerative conditions, respectively.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">But since these findings were observed in sick patients, it remained unclear whether irregular bathroom visits were the cause or result of their conditions.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">&quot;I do hope that this work will kind of open clinicians&#x27; minds a bit to the potential risks of not managing bowel movement frequencies,&quot; senior author Sean Gibbons at the Institute for Systems Biology told AFP, explaining that doctors often view irregular movements as merely a &quot;nuisance.&quot;</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><a href="https://news.abs-cbn.com/news/2024/3/11/diarrhea-heat-exhaustion-doh-sounds-alarm-on-summer-sicknesses-844"></a><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap"><a class="fr-green fr-strong" href="https://news.abs-cbn.com/news/2024/3/11/diarrhea-heat-exhaustion-doh-sounds-alarm-on-summer-sicknesses-844">READ: Diarrhea, heat exhaustion: DOH sounds alarm on summer sicknesses</a></span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">Gibbons and his team collected clinical, lifestyle, and biological data -- including blood chemistry, gut microbiome, genetics and more -- from over 1,400 healthy adult volunteers with no signs of active disease.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">Participants&#x27; self-reported bowel movement frequencies were categorized into four groups: constipation (one or two bowel movements per week), low-normal (three to six per week), high-normal (one to three per day), and diarrhea.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">When stools linger too long in the gut, microbes exhaust the available fiber -- which they ferment into beneficial short-chain fatty acids -- and instead ferment proteins, producing toxins like p-cresol sulfate and indoxyl sulfate.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">&quot;What we found is that even in healthy people who are constipated, there is a rise in these toxins in the bloodstream,&quot; said Gibbons, noting that these toxins are particularly burdensome to the kidneys.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><a href="https://news.abs-cbn.com/lifestyle/2024/5/22/use-of-weight-loss-drugs-soars-among-us-kids-and-young-adults-334"></a><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap"><a class="fr-green fr-strong" href="https://news.abs-cbn.com/lifestyle/2024/5/22/use-of-weight-loss-drugs-soars-among-us-kids-and-young-adults-334">READ: Use of weight-loss drugs soars among US kids and young adults</a></span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap"></span><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap"><strong>- Fruits and vegetables key -</strong></span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">In cases of diarrhea, the team found clinical chemistries indicative of inflammation and liver damage. Gibbons explained that during diarrhea, the body excretes excessive bile acid, which the liver would otherwise recycle to dissolve and absorb dietary fats.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">Fiber-fermenting gut bacteria known as &quot;strict anaerobes,&quot; associated with good health thrived in the &quot;Goldilocks zone&quot; of one or two poops a day. However, Gibbons emphasized that more research is needed to define this optimal range more precisely.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">Demographically, younger people, women, and those with a lower body mass index tended to have less frequent bowel movements.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">Hormonal and neurological differences between men and women may explain the gap, Gibbons said, along with the fact that men generally consume more food.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">Finally, by pairing biological data with lifestyle questionnaires, the team painted a clear picture of those who typically fall into the Goldilocks Zone.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">&quot;It was eating more fruit and vegetables, that was the biggest signal we saw,&quot; said Gibbons, along with drinking plenty of water, regular physical activity, and eating a more plant-dominant diet.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap">The next step in the research could involve designing a clinical trial to manage the bowel movements of a large group of people, followed over an extended period to assess its potential in disease prevention.</span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap"><strong>© Agence France-Presse</strong></span></div><div dir="ltr" style="line-height:1.38;text-align:justify;margin-top:0pt;margin-bottom:10pt"><span style="color:#000000;background-color:transparent;text-decoration:none;vertical-align:baseline;white-space:pre-wrap"><strong>RELATED VIDEO:</strong></span></div><div><span class="fr-video fr-deletable fr-fvc fr-dvb fr-draggable" contenteditable="false" draggable="true"><iframe width="640" height="360" src="https://www.youtube.com/embed/2qpXKPHitTQ?&amp;wmode=opaque&amp;rel=0" frameBorder="0" allowfullscreen="" class="fr-draggable"></iframe></span><br/></div><div><br/></div><div><br/></div>

<p>A new study published Tuesday in Cell Reports Medicine reveals that bowel movement frequency significantly influences physiology and long-term health.</p>

A new study published Tuesday in Cell Reports Medicine reveals that bowel movement frequency significantly influences physiology and long-term health.

One or two bowel movements a day keeps the doc away: study

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One or two bowel movements a day keeps the doc away: study

Agence France-Presse,

Issam Ahmed

Published Jul 17, 2024 06:16 AM PHT

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health

bowel movement

Cell Reports Medicine

Institute for Systems Biology

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